SubscriptionsGo to the Subscriptions Centre to manage your:My Profile”The body makes chemicals that are morphine like, and when you inject [an opioid], it attaches to the same receptor sites in the brain that would be responsive to the chemicals your body makes that are like morphine,” said Daniel Sitar, professor emeritus in the faculty of health sciences at the University of Manitoba.”The effect that you get depends on how fast this chemical gets into the brain and how much gets into the brain in a short period of time.”Fentanyl gets a high amount of chemical into the brain quickly.Fast acting opioids like fentanyl affect opioid receptors in areas that control breathing.Once it’s there, the drug starts attaching to opioid receptors. This kills pain and makes the user feel more calm and less anxious.Opioids like codeine and morphine do this at a much slower rate, so the primary effects are pain relief and reduced anxiety.But, Sitar said, with fast acting opioids like fentanyl, there are other side effects.For one, the drug makes it easier for the brain to release dopamine, which is associated with reward and pleasure.What is Fentanyl?Health agency warns of growing danger to all drug users”The reason people use it is to get that pleasurable sensation and that reduction of anxiety,” said Sitar. “It gives a pleasurable sensation that is actually a side effect of the original intent of the drug for medical purposes.
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